Few programs can directly export Excel spreadsheet (*.xls) as Open Financial Exchange format (*.ofx). However, programs that work with OFX format usually support import of CSV files and you can easily export XLS to CSV, so that is a very easy and viable choice how to achieve XLS to OFX conversion.
Convert Microsoft Excel 97 to 2003 workbook to Open Financial Exchange format.
We found 2 software records in the database related to .xls to .ofx file format conversion.
Microsoft Windows software - convert xls to ofx on Windows
A converter for bank and credit card files
Convert from xls file format
The tables with software actions are a good pointer for what a certain program does with various file types and often may give users a good hint how to perform certain file conversion, for example the above-mentioned xls to ofx. However, it is not perfect and sometimes can show results which are not really usable because of how certain programs work with files and the possible conversion is thus actually not possible at all.
Apple macOS / Mac OS X software - convert xls to ofx on OS X
A spreadsheet application from Apple