LOF is format typically used as digital RAW photograph format in Leica microscopes, thus lof to tiff conversion is usually searched in context of export of these RAWs, to standard graphics formats, for example TIFF.
You cannot do this with standard graphics editors or even photo editors as LOF format is not supported by default. For some tools you might find plugins that add support for .lof files, but otherwise the best approach is to use software designed for this purpose, for example Bio-Formats.
Updated: January 12, 2024