BCL

bcl icon

Illumina CASAVA base call data

File type: Various data file

A bcl file extension identifies base call data produced by Illumina sequencing workflows.

A bcl file belongs to the CASAVA software and contains data from sequencing reads.

Found 2 different file type records with the same bcl filename suffix.

What is bcl file?

File type category:
Various data file

Date updated: November 6, 2026

The bcl file extension is associated with CASAVA, an Illumina application that processes sequencing reads provided by RTA or OLB.

A bcl file is a binary sequencing-run file containing base calls and associated call data. CASAVA uses these files as input during its sequencing data-processing workflow.

CASAVA is legacy Illumina software, and BCL files are mainly encountered in older sequencing runs. The linked CASAVA software is available for Microsoft Windows.

How to open bcl file?

Open the bcl file with CASAVA on Microsoft Windows. It is a binary data file intended for processing by the sequencing workflow rather than for viewing in a text editor.

How to convert bcl file?

CASAVA can process BCL data and export sequencing results in formats used by downstream analysis, such as FASTQ. This is normally performed as part of the CASAVA workflow rather than with a general-purpose file converter.

Because BCL files are instrument and workflow data, they should not be converted by editing or renaming the file extension.

Suggested software to open bcl file:

Associated software actions with the bcl file

Software apps that create bcl files:

Microsoft Windows

Software applications that handle other tasks involving bcl files:

Microsoft Windows

PDP-10 BCPL compiler source

File type category:
Various data file

Date updated: November 9, 2017

Record marked as obsolete and not updated for a long time.

The bcl file extension is associated with the PDP-10 mainframe computer developed by Digital Equipment Corporation.

The bcl file stores data sources for compiler. PDP-10 is obsolete type of computer released in 1968 and used in 1970's.

Related file extensions