An smi file extension is associated with the Daylight SMILES data format.
SMI file extension - Daylight SMILES data
What is smi file? How to open smi files?
File type specification:
The smi file extension is related to the SMILES, a simple yet comprehensive chemical language in which molecules and reactions can be specified using ASCII characters representing atom and bond symbols.
SMILES development was initiated by David Weininger in the late 1980s using the concept of a graph with nodes as atoms and edges as bonds to represent a molecule.
Mime types:
chemical/x-daylight-smiles
chemical/x-x-daylight-smiles
This smi file type entry was marked as obsolete and no longer supported file format.
This type of file is no longer actively used and is most likely obsolete. This is typically the case for system files in old operating systems, file types from long discontinued software, or previous versions of certain file types (like documents, projects etc.) that were replaced in higher versions of their original programs.