An smi file extension is associated with the Daylight SMILES data format.

There are 5 other file types using
the SMI file extension!

empty icon.smi - Microsoft SAMI subtitles

smi icon.smi - IBM Lotus smart icons

smi icon.smi - Mac Self-mounting disk image

empty icon.smi - Siemens mobile phone inbox SMS data

empty icon.smi - Synchronized Multimedia Integration Language presentation

SMI file extension - Daylight SMILES data

What is smi file? How to open smi files?

File type specification:

Various data file type icon Various data file type

The smi file extension is related to the SMILES, a simple yet comprehensive chemical language in which molecules and reactions can be specified using ASCII characters representing atom and bond symbols.


SMILES development was initiated by David Weininger in the late 1980s using the concept of a graph with nodes as atoms and edges as bonds to represent a molecule.

Mime types:
chemical/x-daylight-smiles
chemical/x-x-daylight-smiles

This smi file type entry was marked as obsolete and no longer supported file format.

This type of file is no longer actively used and is most likely obsolete. This is typically the case for system files in old operating systems, file types from long discontinued software, or previous versions of certain file types (like documents, projects etc.) that were replaced in higher versions of their original programs.

Help how to open:

Some specialized programs still support the SMO format and can work with it.

How to convert:

It is unlikely that this file type can be converted to anything else.

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